In vitro potential of equine DEFA1 and eCATH1 as alternative antimicrobial drugs in rhodococcosis treatment.

The equine antimicrobial peptide eCATH1 is effective against the facultative intracellular pathogen Rhodococcus equi in mice.

Rhodococcus equi, the causal agent of rhodococcosis, is a major pathogen of foals and is also responsible for severe infections in immunocompromised humans. Of great concern, strains resistant to currently used antibiotics have emerged. As the number of drugs that are efficient in vivo is limited because of the intracellular localization of the bacterium inside macrophages, new active but cell-...

In vitro potential of equine DEFA 1 and eCATH 1 as alternative 1 antimicrobial drugs in rhodococcosis treatment

In Vitro Cytotoxic Activity of a Lactococcus lactis Antimicrobial Peptide Against Breast Cancer Cells

Background: Nisin, an effective natural food preservative, is an antimicrobial peptide produced by Lactococcus lactis. Although it has been mainly studied and developed as a potential alternative for antibiotics, other pharmacological effects of the nisin including cytotoxic and anti-tumor activity have been attracted many attentions.Objectives: Here, we ...

Status and potential of herbal applications in aquaculture: A review

Disease are recognized as one of the major constraint to sustainable animal production which can cause significant economic loss especially in aquaculture. Various chemotherapeutic agents have been traditionally used in the treatment and prevention of diseases in farmed fish but they are not recommended since improper and continuous use of antibiotics may lead to potential development of antibi...

In Vitro Antimicrobial Potential of the Lichen Parmotrema sp. Extracts against Various Pathogens

  Objective(s):   The ongoing increasing antibiotic resistance is one of the biggest challenges faced by global public health. The perennial need for new antimicrobials against a background of increasing antibiotic resistance in pathogenic and opportunistic microorganisms obliges the scientific community to constantly develop new drugs and antimicrobial agents. Lichens are known pro...